解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::To search for anti-diabetic and insulin-sensitising natural products, the effect on adipocyte differentiation was investigated by assessing fat accumulation in 3T3-L1 preadipocytes using Oil Red O staining. Fractionation and separation of n-hexane and CHCl₃ fractions of Morinda officinalis (Rubiaceae) using several ch...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.608676
更新日期:2012-01-01 00:00:00
abstract::The essential oils of sage leaves (Salvia aucheri Bentham var. canescens Boiss. & Heldr.), growing wild in South Anatolia, were extracted by hydrodistillation and analysed by GC and GC-MS. The percentage yields of the essential oils from sage leaves harvested at different years were 1.0%, 1.3%, 1.3%, 1.0%, 1.4%, 1.5% ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.643309
更新日期:2012-01-01 00:00:00
abstract::Stichopus hermanni and Stichopus vastus are sea cucumber species from the Stichopodidae family within the coastal waters of Malaysia. The integument of these invertebrates is hypothesised to contain abundant glycosaminoglycans (GAGs). GAGs are divided into non-sulphated and sulphated GAGs. Sulphated GAGs have various ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.545354
更新日期:2012-01-01 00:00:00
abstract::The leaves of Alchornea floribunda and Alchornea cordifolia are used traditionally as topical anti-inflammatory agents. In this study, two highly lipophilic fractions AFLF and ACLF isolated from A. floribunda and A. cordifolia leaves respectively were investigated for topical anti-inflammatory effects using xylene-ind...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.512272
更新日期:2011-12-01 00:00:00
abstract::Ocimum is a genus of aromatic herbs, undershurbs or shrubs distributed in the tropical and warm temperate regions of the world. Larvicidal activity of essential oils and different extracts of O. sanctum, O. basilicum and O. gratissimum were compared on laboratory reared and field collected larvae of Culex quinquefasci...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.551755
更新日期:2011-12-01 00:00:00
abstract::The world's rainforests hold untold potential for drug discovery. Rainforest plants are thought to contain evolved defensive active metabolites of greater diversity compared to plants from temperate regions. In recent years, the interest and overall output from pharmaceutical companies on novel antibacterial agents ha...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.537274
更新日期:2011-11-01 00:00:00
abstract::Chromatographic fractionation of the chloroform extracts from the stem bark and stems of Guettarda grazielae resulted in the isolation of a new iridoid (guettardodiol, 1) and the secoiridoid sarracenin (2), described for the first time in this genus. The structural elucidation of these compounds was based on spectrosc...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.507547
更新日期:2011-10-01 00:00:00
abstract::Camptothecin (CPT), the derivatives of which are used clinically for the treatment of metastatic colon cancer, is isolated from intact plants that can be subjected to environmental fluctuations. In vitro cultures may be an alternate and continuous source for year-round production of CPT. Since CPT production by undiff...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.559469
更新日期:2011-10-01 00:00:00
abstract::This study was designed to investigate possible antidepressant-like effects of the extract prepared from the flowers of Hypericum montbretti Spach. (Guttiferae, Clusiaceae). Phytochemical constituents of the methanolic extract were analysed by HPLC method. The main flavonoid component was detected as rutin, and anothe...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.557800
更新日期:2011-09-01 00:00:00
abstract::Chronic administration of myricetin (100 and 300 mg kg⁻¹, p.o., for 4 weeks) isolated from Vitis vinifera (Vitaceae) ameliorated hypertension and oxidative stress induced by deoxycorticosterone acetate (DOCA)-salt in rats. Myricetin treatment reduced systolic blood pressure, vascular reactivity changes and reversed th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903335190
更新日期:2011-09-01 00:00:00
abstract::The cytotoxicity of six ent-kaurene diterpenoids isolated from the leaves of Isodon japonica (Burm.f.) Hara var. galaucocalyx (maxin) Hara was evaluated against three human tumour HepG2, GLC-82 and HL-60 cell lines through SRB assay, and their DNA damage potential (against HepG2 cell line) was assessed by comet assay....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802267734
更新日期:2011-09-01 00:00:00
abstract::Phytochemical investigation of the aerial parts of Eriope blanchetii and E. latifolia (Lamiaceae) yielded podophyllotoxin, as well as the aryltetralin lignans α- and β-peltatin and yatein. Oleanolic, ursolic and epikatonic acids were also isolated. This is the first occurrence of podophyllotoxin in the family. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902809500
更新日期:2011-09-01 00:00:00
abstract::The aim of the present study was to study the effect of seeds of Asteracantha longifolia on the sexual behaviour of male albino rats. The ethanolic extract of seeds of A. longifolia was administered to groups of rats in 100, 150 and 200 mg kg⁻¹ doses for a period of 28 days, and the action compared with control rats. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802588493
更新日期:2011-09-01 00:00:00
abstract::Designing propolis products for external use involves determining the optimal form of propolis for the introduction into dermatological pharmaceuticals and cosmetic preparations. As a potent ingredient, propolis oil extract from raw material harvested in Lithuania was analysed. The rheological characteristics, content...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.529440
更新日期:2011-09-01 00:00:00
abstract::A new carotenoid glycoside, namely neo-rehmannioside (1), together with five known compounds, 6-O-seco-hydroxyaeginetoyl ajugol (2), oxyrehmaionoside B (3), ajugol (4), geniposidic acid (5) and geniposide (6) was isolated from the 95% ethanol extract of dry roots of Rehmannia glutinosa. The structure of the new compou...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.514268
更新日期:2011-08-01 00:00:00
abstract::A simple extraction procedure and HPLC method was developed to analyse the major and minor components of induced phytoalexins of elicited tissues (seeds) of chickpeas (Cicer arietinum L.) and peas (Pisum sativum L.) treated with a biotic elicitor (k-carrageenan) of Hypnea musciformis (red algae) from the Karachi coast...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.553952
更新日期:2011-08-01 00:00:00
abstract::Excessive accumulation of iron in the body can lead to organ injury. Some flavonoids which possess high affinity to iron can be used as iron chelators for curing iron overload diseases such as haemochromatosis. In this article, the effects of baicalin and quercetin on different mouse tissues (liver, kidney and heart) ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.495070
更新日期:2011-07-01 00:00:00
abstract::Plant extracts and products have been used for centuries in traditional medicine; for most of them, in addition to the scant scientific credibility, the chemical composition and spectrum of activity are yet to be explored. To put forward this effort and to identify novel antimicrobial agents, the inhibitory activities...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.529545
更新日期:2011-07-01 00:00:00
abstract::A new furanodihydrobenzoxanthone, artomandin (1), together with three other flavonoid derivatives, artoindonesianin C, artonol B, and artochamin A, as well as β-sitosterol were isolated from the stem bark of Artocarpus kemando. The structures of these compounds were determined on the basis of spectral evidence. All of...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.534471
更新日期:2011-06-01 00:00:00
abstract::A new compound, jolynamine (1), was isolated from the marine brown alga Jolyna laminarioides collected from the coast of Karachi, Pakistan. In addition, four known compounds, namely saringosterol (2), loliolide (3), methyl-4-hydroxybenzoate (4) and propyl-4-hydroxybenzoate (5), were isolated for the first time from th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.509722
更新日期:2011-05-01 00:00:00
abstract::In the present investigation, the anti-inflammatory activity of a polyphenolic enriched extract of Schima wallichii bark was evaluated in vitro using human peripheral blood mononuclear cells (PBMCs) and in vivo by carrageenan-induced paw oedema assay (acute study) and cotton pallet granuloma assay (chronic study). The...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802560732
更新日期:2011-04-01 00:00:00
abstract::The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.536159
更新日期:2011-04-01 00:00:00
abstract::Four xanthones were isolated from Gentianopsis paludosa Ma and were identified by modern spectroscopic methods. Cytotoxicity of the four xanthones was tested on HepG2 cells and HL-60 cells by sulphorhodamine B (SRB) assay. Clonogenic survival assay, trypan blue exclusion method, AO/EB staining and DNA fragmentation as...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802497398
更新日期:2011-04-01 00:00:00
abstract::The essential oil of Cyclospermum leptophyllum (Pers.) Sprague ex Britton and P. Wilson syn. Apium leptophyllum (Pers.) F. Muell. Ex Benth., family Apiaceae (Umbellifereae), was analysed by GC and GC-MS. The essential oil showed the presence of thymohydroquinone dimethyl ether (50.7%), thymol methyl ether (11.2%), γ-t...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.487190
更新日期:2011-03-01 00:00:00
abstract::Benign prostatic hypertrophy (BPH) is a common condition in elderly men that impairs quality of life and leads to a number of medical complications. The use of phytotherapeutic compounds in patients with relatively moderate BPH symptoms has been growing steadily. In the present study, acute toxicity of lyophilised aqu...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802583148
更新日期:2011-02-01 00:00:00
abstract::Triterpene saponins are throught to be potential anti-tumour agents in many cell types. This study aims to evaluate the cytotoxic activity and mechanism of a triterpene saponin, macranthoside B (MB), isolated from Lonicera macranthoides Hand.-Mazz. (Caprifoliaceae). A cell viability assay showed that MB inhibited cell...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003752086
更新日期:2011-02-01 00:00:00
abstract::In this study, the effects of Benzoinum and Styrax on Escherichia coli (E. coli) growth were investigated by microcalorimetry. Using a TAM Air Isothermal Calorimeter, ampoule method, the power-time curves of E. coli growth at 37°C affected by Benzoinum and Styrax were measured. By analysing some quantitative thermokin...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.533670
更新日期:2011-02-01 00:00:00
abstract::Natural estrogens have demonstrated a wide variety of biological activities, which makes them a good candidate for the treatment of diabetes. In vitro, this study evidenced that isoflavones enhanced insulin secretion and inhibited α-amylase activity. In vivo, the findings indicated that soy isoflavones stimulated insu...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003683117
更新日期:2011-02-01 00:00:00
abstract::Terminalia bellerica has been used as a traditional medicine in a variety of ailments including anaemia, asthma, cancer, inflammation, rheumatism and hypertension. In this study, the free radical scavenging and antioxidant activities of methanol extract (ME) and its different solvent fractions (namely hexane (HE), eth...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.482053
更新日期:2011-02-01 00:00:00
abstract::Two new compounds, myrubol (1) and 3-oxo-11α-hydroxyfriedelane (2), were isolated from the roots of Myrica rubra along with eight known compounds (3-10). Their structures were determined through (1)H-NMR and (13)C-NMR spectral data, including 2-D experiments (HMBC, HMQC, (1)H-(1)H COSY and NOESY) and high-resolution m...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.516749
更新日期:2011-01-01 00:00:00
abstract::A minor new withanolide, named plantagiolide F, was isolated from the whole plant of Tacca plantaginea (Hance). The structure of plantagiolide F was elucidated on the basis of spectroscopic methods including extensive 1- and 2-D NMR experiments. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003774304
更新日期:2011-01-01 00:00:00
abstract::Formulations of traditional medicines are usually made up of a complex mixture of herbs. However, effective quality control methods in order to select materials of the right quality are lacking. 'Amukkara choornam' is a polyherbal Siddha formulation used for gastritis, spleen enlargement, leucorrhoea, hiccups, anaemia...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.497147
更新日期:2010-12-01 00:00:00
abstract::Chemical investigation of Trogopterus faeces has led to the isolation of seven flavonoids. Their structures were elucidated by chemical and spectral analyses. In an anticoagulative assay, three kaempferol coumaroyl rhamnosides had significant antithrombin activity. This is the first report on the occurrence of flavono...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.482057
更新日期:2010-11-01 00:00:00
abstract::A new diterpenoid, 15-epi-(4E)-jatrogrossidentadione acetate, along with several known constituents has been isolated from the stem of Jatropha multifida. The structure of the new compound was settled by a detailed analysis of its 1D- and 2D-NMR spectra. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003792207
更新日期:2010-10-01 00:00:00
abstract::Six chemical constituents were isolated from Enicosanthum cupulare (King) Airy-Shaw. The structures of the isolated compounds were determined using 1D, 2D-NMR and were found to be identical to those previously reported for these compounds. Three aporphine alkaloids, O-methylmoschatoline, liriodenine and oxostephanine ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003774338
更新日期:2010-10-01 00:00:00
abstract::The present study was designed to evaluate the herbicidal activity of Datura metel against the noxious weed parthenium (Parthenium hysterophorus L.). In a laboratory bioassay, the effect of aqueous, methanol and n-hexane shoot and root extracts of 5, 10, 15 and 20% w/v (on a fresh weight basis) concentration of D. met...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903075440
更新日期:2010-09-01 00:00:00
abstract::The ethanolic extract of the fruits of Momordica dioica was studied for its protective and curative effect against gentamicin-induced acute renal injury in albino rats of both sexes. Gentamicin intoxicated group showed significant increase in blood urea (69.48 +/- 4.34) and serum creatinine (3.017 +/- 0.208) from norm...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802267569
更新日期:2010-09-01 00:00:00
abstract::The chloroformic extract of the aerial parts of Ferula behboudiana (Umbelliferae) afforded four new polysulphane derivatives: 1-sec-butyl-2-[(E)-3-(methylthio)prop-1-enyl]disulphane (1), 1-sec-butyl-2-[(Z)-3-(methylthio)prop-1-enyl]disulphane (2), 1-[(E)-3-(methylthio)prop-1-enyl)-2-(1-(methylthio)propyl]disulphane (3...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903458273
更新日期:2010-09-01 00:00:00
abstract::The chemical composition of the volatile organic compounds (VOCs) released from the leaves and flowers of Artemisia fragrans Willd. (Asteraceae) was investigated using headspace solid-phase microextraction (HS-SPME) coupled to gas chromatography (GC) and/or GS/mass spectrometry (GC/MS). The efficiency and reliability ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903108951
更新日期:2010-08-01 00:00:00
abstract::The chemical composition of the solvent extracted fixed oil of black cumin (Nigella sativa L.) seeds was determined by capillary GC and GC/MS. Thirty-two fatty acids (99.9%) have been identified in the fixed oil. The major fatty acids were linoleic acid (50.2%), oleic acid (19.9%), margaric acid (10.3%), cis-11,14-eic...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902940909
更新日期:2010-07-01 00:00:00